| Methods |
Trial conducted in Malaysia. |
| Participants |
54 women at 14 to 26 weeks' gestation, with either intrauterine fetal death or fetal anomaly undergoing termination of pregnancy were involved. Women were excluded if a multiple pregnancy, or if there was a contraindication or allergy to the medication. |
| Interventions |
Women were randomised to 1) vaginal misoprostol (200 mcg at 12‐hourly intervals) or 2) vaginal gemeprost (cervagem) (1 mg at 3‐hourly intervals). |
| Outcomes |
Vaginal birth not achieved in 24 hours; induction to delivery interval; analgesic requirements; surgical evacuation of uterus; maternal side effects. |
| Notes |
Method of randomisation: stated that trial was "randomised".
Allocation concealment: sealed opaque envelopes.
Blinding of participants, caregivers, and outcome assessors: not stated. |
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Random sequence generation (selection bias) |
Unclear risk |
Stated that trial was "randomised". |
| Allocation concealment (selection bias) |
Low risk |
Sealed opaque envelopes. |
| Blinding (performance bias and detection bias)
All outcomes |
Unclear risk |
Not stated. |
| Incomplete outcome data (attrition bias)
All outcomes |
Low risk |
|
| Selective reporting (reporting bias) |
Low risk |
|
| Other bias |
Low risk |
|
