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. 2010 Apr 14;2010(4):CD004901. doi: 10.1002/14651858.CD004901.pub2

Zuo 1998.

Methods Trial conducted in China.
Participants 80 women undergoing termination of pregnancy between 13 and 26 weeks' gestation with fetal anomaly. Women excluded if hypersensitive to prostaglandins.
Interventions Women randomised to 1) vaginal misoprostol (200 mcg at 24‐hourly intervals) or 2) Carboprost (1 mg at 3‐hourly intervals).
Outcomes Induction to delivery interval; analgesic requirements; maternal side effects.
Notes Method of randomisation: computer‐generated.
 Allocation concealment: not stated.
 Blinding of participants, caregivers, outcome assessors: not stated.
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Low risk Computer‐generated random number sequence.
Allocation concealment (selection bias) Unclear risk Not stated.
Blinding (performance bias and detection bias) 
 All outcomes Unclear risk Not stated.
Incomplete outcome data (attrition bias) 
 All outcomes Unclear risk Unable to assess.
Selective reporting (reporting bias) Unclear risk Unable to assess.
Other bias Unclear risk Unable to assess.

GTN:glyceryl trinitrate
 mcg: micrograms
 mg: milligrams
 mL: millilitres
 PGE2: prostaglandin E2
 VAS: visual analogue scale
 vs: versus