Zuo 1998.
Methods | Trial conducted in China. | |
Participants | 80 women undergoing termination of pregnancy between 13 and 26 weeks' gestation with fetal anomaly. Women excluded if hypersensitive to prostaglandins. | |
Interventions | Women randomised to 1) vaginal misoprostol (200 mcg at 24‐hourly intervals) or 2) Carboprost (1 mg at 3‐hourly intervals). | |
Outcomes | Induction to delivery interval; analgesic requirements; maternal side effects. | |
Notes | Method of randomisation: computer‐generated. Allocation concealment: not stated. Blinding of participants, caregivers, outcome assessors: not stated. | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Low risk | Computer‐generated random number sequence. |
Allocation concealment (selection bias) | Unclear risk | Not stated. |
Blinding (performance bias and detection bias) All outcomes | Unclear risk | Not stated. |
Incomplete outcome data (attrition bias) All outcomes | Unclear risk | Unable to assess. |
Selective reporting (reporting bias) | Unclear risk | Unable to assess. |
Other bias | Unclear risk | Unable to assess. |
GTN:glyceryl trinitrate mcg: micrograms mg: milligrams mL: millilitres PGE2: prostaglandin E2 VAS: visual analogue scale vs: versus