Comparison 3.

Efficacy: Vertebroplasty versus kyphoplasty (balloon)

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Pain (0 to 10 point scale)	6		Mean Difference (IV, Random, 95% CI)	Subtotals only
1.1 1 to 2 weeks	2	462	Mean Difference (IV, Random, 95% CI)	‐0.06 [‐0.37, 0.25]
1.2 1 month	2	441	Mean Difference (IV, Random, 95% CI)	‐0.05 [‐0.59, 0.48]
1.3 3 months	2	419	Mean Difference (IV, Random, 95% CI)	0.14 [‐0.11, 0.39]
1.4 6 months	3	230	Mean Difference (IV, Random, 95% CI)	‐0.04 [‐0.31, 0.22]
1.5 12 months	4	558	Mean Difference (IV, Random, 95% CI)	0.16 [‐0.07, 0.40]
1.6 24 months	2	320	Mean Difference (IV, Random, 95% CI)	‐0.15 [‐0.56, 0.27]
2 Disability (ODI)	4	1758	Std. Mean Difference (IV, Random, 95% CI)	‐0.03 [‐0.12, 0.07]
2.1 1 to 2 weeks	1	98	Std. Mean Difference (IV, Random, 95% CI)	0.02 [‐0.38, 0.41]
2.2 1 month	2	425	Std. Mean Difference (IV, Random, 95% CI)	‐0.11 [‐0.30, 0.08]
2.3 3 months	2	399	Std. Mean Difference (IV, Random, 95% CI)	0.04 [‐0.16, 0.24]
2.4 6 months	1	93	Std. Mean Difference (IV, Random, 95% CI)	‐0.06 [‐0.46, 0.35]
2.5 12 months	4	542	Std. Mean Difference (IV, Random, 95% CI)	0.00 [‐0.16, 0.17]
2.6 24 months	1	201	Std. Mean Difference (IV, Random, 95% CI)	‐0.07 [‐0.35, 0.21]
3 Quality of Life (EQ5D)	2	1346	Std. Mean Difference (IV, Random, 95% CI)	0.06 [‐0.04, 0.17]
3.1 1 month	2	422	Std. Mean Difference (IV, Random, 95% CI)	0.10 [‐0.09, 0.29]
3.2 3 months	1	292	Std. Mean Difference (IV, Random, 95% CI)	0.0 [‐0.23, 0.23]
3.3 6 months	1	88	Std. Mean Difference (IV, Random, 95% CI)	0.03 [‐0.39, 0.45]
3.4 12 months	2	342	Std. Mean Difference (IV, Random, 95% CI)	0.06 [‐0.15, 0.27]
3.5 24 months	1	202	Std. Mean Difference (IV, Random, 95% CI)	0.10 [‐0.18, 0.37]