Comparison 5.

Safety: Vertebroplasty versus placebo (sham) or usual care

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 New clinical vertebral fractures	7	1020	Risk Ratio (M‐H, Random, 95% CI)	1.08 [0.62, 1.87]
2 New radiographic vertebral fractures	7	662	Risk Ratio (M‐H, Random, 95% CI)	1.20 [0.67, 2.15]
3 Number of serious other adverse events	5	821	Risk Ratio (M‐H, Random, 95% CI)	0.64 [0.36, 1.12]