Table 2. Platelet-specific data for all trauma patients at hour 0, stratified by the presence of TIC.
Data are presented as median (interquartile range). P-values obtained by Wilcoxon rank-sum test. REF, reference range; AUC, area under the curve.
| Lab Value | No TIC (n=80) | TIC (n=15) | P |
|---|---|---|---|
| Platelet count, x109/L (REF 150–450) | 231 (187–279) | 211 (156–250) | 0.162 |
| PFA-100 collagen/epinephrine closure time, sec (REF <180) |
97 (84–126) | 155 (119–300) | 0.002 |
| PFA-100 collagen/ADP closure time, sec (REF <120) | 64 (54–81) | 70 (49–129) | 0.613 |
| Platelet ADP aggregation, ohms (REF 6–24) | 11.0 (8.5–13.0) | 6.0 (3.5–8.5) | 0.001 |
| Platelet collagen aggregation, ohms (REF 14–28) | 14.5 (12.0–18.0) | 12.0 (6.5–13.5) | 0.002 |
| Platelet Contractile Force, Kdynes | 8.0 (6.6–9.4) | 6.0 (5.0–8.7) | 0.029 |
| TEG-PM ADP inhibition, % | 78.7 (57.8–97.0) | 96.1 (65.2–97.3) | 0.292 |
| TEG-PM AA inhibition, % | 38.9 (19.6–65.8) | 35.1 (13.7–52.0) | 0.356 |
| Percent PAC-1-positive | 6.0 (1.8–12.6) | 3.5 (0.5–10.2) | 0.265 |
| Percent CD62P-positive | 3.0 (1.4–7.8) | 2.6 (0.8–5.7) | 0.268 |
| Percent that became CD62P-positive after ADP stimulation |
70.1 (57.5–76.8) | 72.5 (63.2–77.2) | 0.914 |