Table 3. Descriptive characteristics of the 50 patients included in the longitudinal data analysis.

Data are presented as median (interquartile range). P-values obtained by Wilcoxon rank-sum test.

	All Included Patients (n=50)	No TIC (n=38)	TIC (n=12)	P
Demographics/Vital Signs
Age, years	37 (24–53)	44 (25–54)	27.5 (23.5–42.5)	0.149
Heart Rate, beats per min	100 (84–116)	98 (80–108)	117 (104–135)	0.011
Systolic Blood Pressure, mmHg	127.5 (112–151)	132 (118–153)	112 (94–116)	0.005
Diastolic Blood Pressure, mmHg	76.5 (61–92)	81 (64–96)	61 (49.5–77)	0.006
Respiratory Rate, breaths per min	18.5 (15–24)	18 (14–24)	20 (17.5–25)	0.487
Oxygen Saturation, %	99 (97–100)	99 (97–100)	99 (96–100)	0.812
Temperature, °C	36.3 (35.9–36.7)	36.3 (36.0–36.8)	36.0 (35.5–36.5)	0.260
Injury Severity Score	22 (14–30)	19 (13–29)	28.5 (21–42)	0.012
Glasgow Coma Score	13.5 (3–15)	14.5 (3–15)	7 (3–14)	0.144
Laboratory Values
[Lactate], mmol/L	4.4 (2.8–5.2)	3.8 (2.7–4.9)	5.2 (4.5–11.2)	0.007
Base Deficit, mEq/L	3.1 (1.0–6.5)	2.2 (0.7–4.8)	7.8 (3.9–13.6)	<0.001
Hemoglobin, g/dL	13.3 (11.8–14.4)	13.9 (12.5–14.9)	11.0 (10.2–13.0)	<0.001
Hematocrit, %	36.5 (32.5–41.0)	38.6 (35.3–43.6)	32.3 (30.4–35.9)	0.004
Platelet Count, x109/L	236 (177–279)	243 (179–284)	217 (151–265)	0.156
PT, sec	15.1 (14.0–17.7)	14.7 (13.7–15.3)	20.2 (19.3–21.2)	<0.001
aPTT, sec	33.5 (29.5–38.2)	32.3 (29.0–35.7)	39.0 (32.6–46.1)	0.007
Crystalloid Fluid Resuscitation, mL
Total Crystalloid Given at Hour 0	1500 (500–2000)	1200 (350–2000)	2100 (2000–3000)	0.003
Total Crystalloid Given at Hour 8	550 (0–2700)	547 (0–2660)	1668 (253–4090)	0.520
Blood Products at Hour 8, mL
Total Blood Products	0 (0–620)	0 (0–310)	1400 (310–2555)	<0.001
Packed Red Blood Cells	0 (0–620)	0 (0–310)	930 (310–1550)	<0.001
Fresh Frozen Plasma	0 (0–0)	0 (0–0)	225 (0–788)	<0.001
Pooled Platelets	0 (0–0)	0 (0–0)	20 (0–200)	<0.001
Apheresis Platelets	0 (0–0)	0 (0–0)	0 (0–0)	0.011
Cryoprecipitate	0 (0–0)	0 (0–0)	20 (0–200)	0.015