Table 1.
Patient Demographics
BSO bilateral salpingo-oophorectomy
| Clinically detected (n = 22) | Screen-detected (n = 92) | P-value | Interval cancers (n = 11) | Screen-detected (n = 64) | P-value | |
|---|---|---|---|---|---|---|
| All Women | Regular Screeners | |||||
| Age at diagnosis, median (range) | 42 (28, 65) | 49 (27, 72) | 0.01 | 41 (28, 65) | 51 (30, 72) | 0.02 |
| Age at genetic testing, median (range) | 36 (23, 60) | 45 (23, 71) | 0.01 | 36 (26, 60) | 48 (23, 71) | 0.07 |
| Race | < .01 | 0.03 | ||||
| Caucasian | 17 (77%) | 86 (94%) | 9 (82%) | 59 (92%) | ||
| Black | 4 (18%) | 0 (0%) | 2 (18%) | 0 (0%) | ||
| Asian | 0 (0%) | 4 (4%) | 0 (0%) | 4 (6%) | ||
| Other | 1 (5%) | 0 (0%) | 0 (0%) | 0 (0%) | ||
| Unknown | 0 (0%) | 2 (2%) | 0 (0%) | 1 (2%) | 0.03 | |
| Body mass index, median (range) | 24 (19, 32) | 27 (18, 46) | 0.01 | 24 (19, 29) | 27 (18, 46) | 0.02 |
| BRCA mutation | 0.13 | 0.22 | ||||
| BRCA1 | 16 (73%) | 54 (59%) | 7 (64%) | 35 (55%) | ||
| BRCA2 | 5 (23%) | 37 (40%) | 3 (27%) | 28 (44%) | ||
| Both | 1 (5%) | 1 (1%) | 1 (9%) | 1 (2%) | ||
| BSO | 6 (27%) | 50 (49%) | 0.03 | 4 (36%) | 41 (64%) | 0.10 |
| Family history of breast cancer | 22 (100%) | 83 (90%) | 0.2 | 11 (100%) | 58 (91%) | 0.6 |