. Author manuscript; available in PMC: 2020 May 1.

Published in final edited form as: Pediatr Res. 2018 Nov 12;85(6):799–806. doi: 10.1038/s41390-018-0229-z

Table 3.

Associations of maternal pre-pregnancy BMI category with markers of inflammation during pregnancy

Outcome	BMI category (kg/m²)	Unadjusted β (95% CI)	Adjusted^a β (95% CI)
2^nd trimester CRP, mg/L	18.5-<25.0	0.0 (ref)	0.0 (ref)
	25.0-<30.0	0.5 (0.3, 0.7)	0.5 (0.3, 0.7)
	≥30.0	1.0 (0.7, 1.3)	0.9 (0.6, 1.2)
2^nd trimester plasma n6:n3	18.5-<25.0	0.0 (ref)	0.0 (ref)
	25.0-<30.0	0.6 (0.0, 1.2)	0.5 (−0.1, 1.1)
	≥30.0	1.7 (0.7, 2.6)	1.4 (0.5, 2.4)
Mean 1^st+2^nd trimester DII, units	18.5-<25.0	0.0 (ref)	0.0 (ref)
	25.0-<30.0	0.3 (0.1, 0.4)	0.1 (0.0, 0.3)
	≥30.0	0.5 (0.3, 0.8)	0.2 (0.0, 0.4)

CRP: C-reactive protein. n-6:n-3: omega-6: omega-3. DII: Dietary Inflammatory Index.

Adjusted for maternal age at enrollment, race/ethnicity, education, pre-pregnancy smoking status, parity, and household income.