Table 2.
Simulation results for human exposures and severe adverse events from three different campaign situations.
| Vaccine use | Human Exposures Mean (95% CI); Median (Med); Range (R); Sensitivity Analysis Range (SR) | Exposure-prompted visits to health care facilities Mean (95% CI); Med; R; SI | Exposure-associated deaths | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Total | Mucosal contact | Transdermal contact | Transdermal bite | Severe bite | Lick | Bite from rabid animal | Total | Total Count | Rate | |
| Mean (95% CI); Med; R; SI | Rate per 10 million baits (95% CI) | |||||||||
|
SAD B19
(Foxes as targets) |
3.31 (0,12) | 1.05 (0,3) | 1.13 (0,3) | 1.11 (0,5) | 0 (0,0) | 0.004 (0,1) | 0.017 (0,1) | 1.59 (0,6) | 0.007 (0,1) | 0.18 (0.08, 0.36) |
| Med: 3 | Med: 1 | Med: 1 | Med: 1 | Med: 0 | Med: 0 | Med: 0 | Med: 1 | Med: 0 | ||
| R: 0–23 | R: 0–5 | R: 0–8 | R: 0–8 | R: 0 | R: 0–1 | R: 0–2 | R: 0–11 | R: 0–1 | ||
| SR: 0–333 | SR: 0–91 | SR: 0–147 | SR: 0–162 | SR: 0–1 | SR: 0–8 | SR: 0–2 | SR: 0–155 | SR: 0–19 | ||
|
SAD-B19
(Dogs as targets) |
21.50 (2,54) | 1.01 (0,5) | 1.09 (0,6) | 17.65 (1,51) | 0 (0,0) | 0.06 (0,1) | 1.68 (0,7) | 12.54 (1,33) | 0.13 (0,1) | 3.35 (2.83, 3.98) |
| Med: 18 | Med: 0 | Med: 0 | Med: 15 | Med: 0 | Med: 0 | Med: 1 | Med: 18 | Med: 0 | ||
| R: 0–68 | R: 0–12 | R: 0–12 | R: 0–64 | R: 0–1 | R: 0–2 | R: 0–13 | R: 0–45 | R: 0–2 | ||
| SR: 1–219 | SR: 0–191 | SR: 0–165 | SR: 0–142 | SR: 0–1 | SR: 0–6 | SR: 0–46 | SR: 0–127 | SR: 0–61 | ||
|
GASGAS
(Dogs as targets) |
19.37 (2,54.2) | 0.45 (0,3) | 0.43 (0,3) | 18.42 (1,54) | 0 (0,0) | 0.06 (0,1) | 0 (0,0) | 11.36 (1,32) | 0 (0,0) | 0 (0, 0.12) |
| Med: 17 | Med: 0 | Med: 0 | Med: 16 | Med: 0 | Med: 0 | Med: 0 | Med: 9 | Med: 0 | ||
| R: 2–87 | R: 0–8 | R: 0–5 | R: 0–87 | R: 0 | R: 0–2 | R: 0 | R: 0–51 | R: 0 | ||
| SR: 1–1,128 | SR: 0–144 | SR: 0–128 | SR: 1–1,046 | SR: 0 | SR: 0–9 | SR: 0 | SR: 0–775 | SR: 0–1 | ||