Table 1.
Mean weight (in grams) of Myotis lucifugus that received various treatments prior to challenge with Pseudogymnoascus destructans (Pd) and post-challenge survival.
| Treatment | Route | n | % survival after challenge | Mean weight at challenge (g) ± s.d. |
|---|---|---|---|---|
| PBS | IM | 3 | 0 | 8.68 ± 0.21 |
| CAL | IP | 7 | 0 | 7.95 ± 1.22 |
| RCN-CAL | IN | 8 | 25 | 9.09 ± 1.12 |
| RCN-CAL/RCN-SP | IM | 10 | 10 | 8.23 ± 1.28 |
| Inactivated Pd | IM | 9 | 44 | 9.62 ± 1.38 |
Treatments included phosphate buffered saline (PBS) as a negative control, calnexin (CAL) protein, raccoon poxvirus (RCN) expressing CAL, RCN expressing CAL and RCN expressing serine protease (SP) in combination, and inactvated Pd, administered via intramuscular (IM), intraperitoneal (IP), or intranasal (IN) routes.