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. 2019 May 1;2:153. doi: 10.1038/s42003-019-0413-7

Table 2.

Pairwise correlation analysis of subunit gene expression across levels, from single cell to global brain expression

Positive correlations Negative correlations
Gene Gene Subunits From datasets Cell class (C,D) Gene Gene Subunits Cell class (C,D)
GABRA1 GABRB2 α1−β2 A,B,C,D Exc, 1 Inh GABRA1 GABRA2 α1, α2 B,C,D 9 Exc, 2 Inh
GABRA1 GABRD α1−δ B,D 1 Exc GABRA1 GABRA3 α1, α3 B,D 1 Exc
GABRA2 GABRA4 α2α4 A,C Exc, Inh GABRA1 GABRA4 α1, α4 C,D 4 Exc, 2 Inh
GABRA2 GABRB1 α2−β1 A,B GABRA1 GABRA5 α1, α5 D 2 Exc, 1 Inh
GABRA2 GABRB3 α2−β3 A,D 1 Inh GABRA1 GABRB1 α1, β1 A,B,C,D 1 Exc, 1 Inh
GABRA3 GABRB1 α3−β1 A,B,C,D 1 Exc GABRA1 GABRB3 α1, β3 A,C
GABRA4 GABRB2 α4−β2 B,D 1 Exc GABRA1 GABRG1 α1, γ1 A,B,C
GABRA4 GABRD α4−δ B,C Exc GABRA2 GABRA4 α2, α4 B,D 1 Exc
GABRB1 GABRB3 β1−β3 A,C Inh GABRA2 GABRB2 α2, β2 B,C,D 1 Exc, 1 Inh
GABRB1 GABRG1 β1−γ1 A,B GABRA2 GABRG2 α2, γ2 B,D 1 Inh
GABRA3 GABRD α3, δ A,B
GABRA5 GABRB2 α5, β2 B,C Inh
GABRA5 GABRG2 α5, γ2 B,C
GABRA5 GABRG2 α5, δ B,C
GABRB1 GABRB2 β1, β2 A,B,C,D 2 Exc, 4 Inh
GABRB1 GABRB3 β1, β3 D 2 Exc
GABRB1 GABRAD β1, δ A,B,C,D 1 Exc
GABRB2 GABRB3 β2, β3 D 11 Exc, 3 Inh
GABRB2 GABRG1 β2, γ1 A,B,C,D 1 Exc
GABRB3 GABRG2 β3, γ2 C,D 1 Inh
GABRG1 GABRG2 γ1, γ2 B,D 4 Exc
GABRG1 GABRD γ1, δ A,B
GABRG2 GABRD γ2, δ A,D 4 Exc, 3 Inh

Dataset A: Allen Atlas Microarray study, Dataset B: Aging, Dementia and Traumatic Brain Injury study, Datasets C and D: Allen Institute Cell-type study across excitatory and inhibitory cells and within each cell-type cluster, respectively. Cell class was determined from datasets C and D. Subunits in bold indicate pairs with positive and negative correlations across different analyses