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. 2019 May 1;9:6767. doi: 10.1038/s41598-019-43047-3

Figure 4.

Figure 4

CPT treatment neither enhances nor exerts antiviral activity against MV infection. (A) Schematic representations of the time-of-drug-addition analysis on CPT treatment against MV infection. (B) Pre-treatment effect of CPT on MCF-7 cells before MV infection. (C) Co-addition treatment effect of CPT on MV infection of MCF-7 cells. (D) Post-infection treatment effect of CPT on MCF-7 cells immediately after MV infection. Results were obtained after 3 days of incubation. (E) Viral titer readouts of CPT treatment at different time-points of MV infection as in (B–D). For all experiments, MV infection was performed at MOI 0.1, DMSO (0.1%) was included as negative control, and IFN-α (1,000 IU/ml) was included as positive control treatment where indicated. All data shown are means ± SEM (*P < 0.05) from three independent experiments.