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. 2018 Dec 26;28(10):1594–1607. doi: 10.1093/hmg/ddy448

Figure 3.

Figure 3

GRP75 protein levels are decreased in both FRDA patient skin fibroblasts and buccal cells. FRDA patient skin fibroblasts or buccal cells were lysed and subjected to western blotting with the indicated antibodies. The amount of immunoreactivity in the lysates was quantified as a percentage of the controls. Representative blots and bar graphs demonstrate reduced frataxin in both fibroblasts (A and B) (n = 3) and buccal cells (C and D) (n = 20 for patients and n = 7 for controls). Accordingly, GRP75 was also decreased in both fibroblasts (A, B) (n = 3) and buccal cells (C, D) (n = 20 for patients and n = 7 for controls). *P < 0.05; **P < 0.01. Data were shown as mean ± SE.