. 2018 Dec 26;28(10):1594–1607. doi: 10.1093/hmg/ddy448

Table 1.

GRP75 overexpression increases frataxin variants

		Fold increase
Variants	Precursor	Intermediate	Mature	Number
G130V	11.9^*	1.52^*	1.55^*	5
W155R	9.42^*	1.56^*	0.85^*	5
I154F	19^*	0.51^*	0.54^*	5
G137V	6.4^*	1.5^*	1.19^*	7
W168R	58^*	4.98^*	1.12^*	5
L106S	12.55^*	2.37^*	Unchanged	5
R165C	7.69^*	Unchanged	Unchanged	5

Precursor, intermediate and mature forms in HEK293 cells co-transfected with frataxin variants and GRP75 were quantified and listed as fold increase over vector control. ^*P < 0.05.