Table 2.
Comparison of Retraced Definite Resister Phenotype and Latent M.tb Infection Tuberculosis Contacts
| RSTRs (N = 82) |
LTBI (N = 194) |
OR | P-Value | |
|---|---|---|---|---|
| % Female | 47.6% | 48.5% | 0.977 | .937 |
| Current age (mean, SD) | 22.9 (10.1) | 24.12 (9.1) | 0.975 | .237 |
| Time since phase 1 enrolment (median, SD) | 9.2 (3.5) | 9.4 (3.2) | 0.982 | .693 |
| % BCG vaccinated | 62.2% | 69.1% | 0.783 | .471 |
| Epi risk score - children (median, SD)a | 6.00 (.9) | 6.00 (.8) | 0.867 | .531 |
| Epi risk score - adults (median, SD)a | 6.00 (1.1) | 6.00 (1.3) | 0.839 | .316 |
| Current BMI (mean, SD) | 22.3 (4.0) | 23.3 (4.8) | 0.965 | .305 |
| Contact with TB since original study | 0% | 2.6% | NA | .326 |
Abbreviations: BCG, bacille Calmette-Guérin; BMI, body mass index; Epi, epidemiologic; LTBI, latent M.tb infection; NA, not applicable; OR, odds ratio; RSTR, resister phenotype; SD, standard deviation; TB, tuberculosis.
aRisk score was generated based on the age of the contact during the original TB household contact study (phase 1); age determined the values of the score’s variables (eg, proximity to and characteristics of the index case). Analysis was stratified by age in phase 1, with children defined as <15 years old.