Table 3.
Clinical Signs per Case Definition of Congenital Rubella Syndrome Cases Identified at Sentinel Surveillance Sites, South Africa, 2010–2017
| Clinical Characteristic n (%) | 2010–2014 (N = 42) | 2015–2017 (N = 53) |
|---|---|---|
| Congenital heart disease | ||
| Yes | 30 (71%) | 43 (81%) |
| No | 3 (7%) | 3 (6%) |
| Unknown | 9 (22%) | 7 (13%) |
| Cataract | ||
| Yes | 22 (52%) | 28 (53%) |
| No | 8 (19%) | 15 (28%) |
| Unknown | 12 (29%) | 10 (19%) |
| Glaucoma | ||
| Yes | 1 (2%) | 2 (4%) |
| No | 15 (36%) | 20 (38%) |
| Unknown | 26 (62%) | 31 (58%) |
| Hearing impairment | ||
| Yes | 5 (12%) | 3 (6%) |
| No | 6 (14%) | 2 (4%) |
| Unknown | 31 (74%) | 48 (90%) |
| Hepatosplenomegaly | ||
| Yes | 16 (38%) | 26 (49%) |
| No | 6 (14%) | 17 (32%) |
| Unknown | 20 (48%) | 10 (19%) |
| Jaundice | ||
| Yes | 3 (7%) | 10 (19%) |
| No | 7 (17%) | 26 (49%) |
| Unknown | 32 (76%) | 17 (32%) |
| Meningoencephalitis | ||
| Yes | 2 (5%) | 7 (13%) |
| No | 11 (26%) | 24 (45%) |
| Unknown | 29 (69%) | 22 (42%) |
| Mental Retardation | ||
| Yes | 9 (21%) | 2 (4%) |
| No | 4 (10%) | 4 (8%) |
| Unknown | 29 (69%) | 47 (88%) |
| Microcephaly | ||
| Yes | 10 (24%) | 23 (43%) |
| No | 11 (26%) | 14 (27%) |
| Unknown | 21 (50%) | 16 (30%) |
| Pigmentary retinopathy | ||
| Yes | 0 (0%) | 2 (4%) |
| No | 14 (33%) | 14 (26%) |
| Unknown | 28 (67%) | 37 (70%) |
| Purpura | ||
| Yes | 3 (7%) | 13 (24%) |
| No | 8 (19%) | 28 (53%) |
| Unknown | 31 (74%) | 12 (23%) |
| Radiolucent bone disease | ||
| Yes | 0 (0%) | 5 (9%) |
| No | 6 (14%) | 16 (30%) |
| Unknown | 36 (86%) | 32 (61%) |