Table 3.

ROC Curve Analyses of Serum miRNAs for Distinguishing Oral Cancer Patients from Normal Controls

	AUC	Sensitivity	Specificity	p Value	95% CI
miR-99a-5p	0.521	86.6%	24.5%	0.680	0.421–0.622
miR-31-5p	0.661	69.8%	52.4%	0.002	0.564–0.758
miR-138-5p	0.547	67.9%	51.2%	0.360	0.448–0.646
miR-21-5p	0.579	64.2%	46.3%	0.123	0.483–0.675
miR-375-3p	0.514	60.4%	50.0%	0.787	0.413–0.614
Combinationa	0.776	76.8%	73.6%	0.000	0.695–0.857

CI, confidence interval

^aCombination of miR-99a-5p, miR-31-5p, miR-138-5p, miR-21-5p, and miR-375-3p