Table 3.
α-Glucosidase inhibitory activities of compounds 1−16 a .
| Compound | α-glucosidase inhibitory activityb |
|
|---|---|---|
| 750 μM (%) | IC50 ± SD (μM) | |
| 1 | 37.4 ± 1.4 | N.T. |
| 2 | 42.0 ± 2.7 | N.T. |
| 4 | 49.9 ± 1.8 | N.T. |
| 5 | 93.4 ± 3.1 | 112.3 ± 4.5 |
| 7 | 86.9 ± 0.4 | 407.0 ± 3.3 |
| 8 | 77.3 ± 1.0 | 524.5 ± 2.7 |
| 9 | 48.9 ± 1.1 | N.T. |
| 10 | 92.1 ± 3.4 | 218.8 ± 5.6 |
| acarbosec | 50.7 ± 1.2 | 743. 4 ± 3.3 |
aCompounds 3, 6, and 11−16 were inactive toward α-glucosidase at 750 μM (inhibition rate <30%). bValues represent means ± SD based on three individual experiments. cPositive control. N.T.: not tested.