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. 2019 Apr 22;34(1):853–862. doi: 10.1080/14756366.2019.1576657

Table 3.

α-Glucosidase inhibitory activities of compounds 116 a .

Compound α-glucosidase inhibitory activityb
750 μM (%) IC50 ± SD (μM)
1 37.4 ± 1.4 N.T.
2 42.0 ± 2.7 N.T.
4 49.9 ± 1.8 N.T.
5 93.4 ± 3.1 112.3 ± 4.5
7 86.9 ± 0.4 407.0 ± 3.3
8 77.3 ± 1.0 524.5 ± 2.7
9 48.9 ± 1.1 N.T.
10 92.1 ± 3.4 218.8 ± 5.6
acarbosec 50.7 ± 1.2 743. 4 ± 3.3

aCompounds 3, 6, and 1116 were inactive toward α-glucosidase at 750 μM (inhibition rate <30%). bValues represent means ± SD based on three individual experiments. cPositive control. N.T.: not tested.