Table 1.
Running speed is not affected by optogenetic silencing of MSDB neurons
| Group | Mean ± SD |
n | Df; factor, error | F statistic | p | |||
|---|---|---|---|---|---|---|---|---|
| Running speed before laser stimulation, cm/s | Running speed during laser stimulation, cm/s | Running speed after laser stimulation, cm/s | ||||||
| Average across mice | Laser control | 8.24 ± 3.23 | 8.09 ± 3.36 | 8.74 ± 3.82 | 7 | 2, 18 | 0.07 | 0.93 |
| GFP control | 6.35 ± 1.11 | 6.44 ± 1.41 | 6.32 ± 1.06 | 5 | 2, 12 | 0.01 | 0.99 | |
| ChAT-Cre | 8.41 ± 3.62 | 8.76 ± 3.27 | 8.72 ± 3.73 | 10 | 2, 27 | 0.03 | 0.97 | |
| Average across sessions | Wild-type, ArchT | 7.29 ± 3.65 | 7.25 ± 3.84 | 7.51 ± 3.63 | 15 | 2, 42 | 0.02 | 0.98 |
| 3.43 ± 1.34 | 3.23 ± 1.08 | 4.57 ± 1.97 | 11 | 2, 30 | 2.53 | 0.10 | ||
| 10.53 ± 1.84 | 12.26 ± 2.49 | 12.13 ± 2.88 | 9 | 2, 24 | 1.41 | 0.26 | ||
| 9.51 ± 3.43 | 8.06 ± 2.31 | 11.99 ± 6.97 | 9 | 2, 24 | 1.63 | 0.22 | ||
| PV-Cre | 9.67 ± 4.95 | 10.00 ± 5.45 | 9.73 ± 4.74 | 4 | 2, 9 | 0 | 1.00 | |
| 10.27 ± 3.17 | 10.94 ± 2.92 | 10.46 ± 2.94 | 9 | 2, 24 | 0.12 | 0.89 | ||
| 13.43 ± 4.98 | 11.03 ± 3.33 | 11.70 ± 3.82 | 5 | 2, 12 | 0.46 | 0.65 | ||
| vGluT2-Cre | 6.73 ± 1.91 | 6.19 ± 1.69 | 5.61 ± 1.49 | 5 | 2, 12 | 0.53 | 0.60 | |
| 7.77 ± 2.17 | 7.13 ± 1.20 | 6.89 ± 1.88 | 24 | 2, 69 | 1.55 | 0.22 | ||
| 6.04 ± 1.90 | 5.07 ± 2.01 | 5.78 ± 1.32 | 10 | 2, 27 | 0.80 | 0.46 | ||
Df, Degrees of freedom; n, sample size. Statistics were performed across mice if the number of mice ≥5, otherwise across sessions per mouse.