Table 2.
Changes in theta peak power during optogenetic silencing
Group | Change in theta peak amplitude, % |
n | Df | t Statistic | p | Effect size, Cohen's d | |
---|---|---|---|---|---|---|---|
Mean ± SD | |||||||
Average across mice | Laser control | 3.69 ± 18.57 | 6 | 5 | 0.487 | 0.647 | 0.20 |
GFP control | 12.38 ± 28.3 | 5 | 4 | 0.978 | 0.383 | 0.44 | |
ChAT-Cre | 25.36 ± 45.94 | 10 | 9 | 1.746 | 0.115 | 0.55 | |
Average across sessions | Wild-type, ArchT | −19.57 ± 29.11 | 15 | 14 | −2.603 | 0.021 | 0.67 |
−52.95 ± 27.38 | 8 | 7 | −5.470 | 0.001 | 1.93 | ||
−54.50 ± 26.98 | 9 | 8 | −6.060 | 0.000 | 2.02 | ||
−61.60 ± 16.22 | 9 | 8 | −11.295 | 0.000 | 3.80 | ||
PV-Cre | −40.49 ± 13.13 | 3 | 2 | −5.341 | 0.033 | 3.08 | |
−68.59 ± 21.85 | 6 | 5 | −7.690 | 0.001 | 3.14 | ||
−27.52 ± 11.77 | 5 | 4 | −5.227 | 0.006 | 2.34 | ||
vGluT2-Cre | −6.97 ± 27.19 | 5 | 4 | −0.573 | 0.597 | 0.26 | |
8.49 ± 15.39 | 24 | 23 | 2.703 | 0.013 | 0.55 | ||
18.33 ± 19.18 | 10 | 9 | 3.021 | 0.014 | 0.96 |
Df, Degrees of freedom; n, sample size. Statistics were performed across mice if the number of mice ≥5, otherwise across sessions per mouse.