Table 1.
Frequency | Age | Parameter | X1 (mean ± SEM) | Xmax(min) (mean ± SEM) | p | Stimulus no. | n |
---|---|---|---|---|---|---|---|
10 Hz | P4 | S | 1.55 ± 0.43 | 4.79 ± 1.07 | 9.9e−06 | 7 | 13 |
Psuccess | 0.07 ± 0.02 | 0.19 ± 0.03 | 2.3e−05 | ||||
A | 21.88 ± 2.17 | 21.58 ± 3.27 | 0.9965 | ||||
P6–P7 | S | 8.31 ± 1.05 | 16.44 ± 2.47 | 3.6e−05 | 4 | 12 | |
Psuccess | 0.43 ± 0.05 | 0.61 ± 0.06 | 0.0022 | ||||
A | 19.52 ± 0.84 | 26.24 ± 2.37 | 0.289 | ||||
P9–P11 | S | 24.18 ± 3.23 | 16.09 ± 2.86 | 7.6e−08 | 8 | 20 | |
Psuccess | 0.72 ± 0.06 | 0.55 ± 0.07 | 2.6e−06 | ||||
A | 31.50 ± 2.25 | 25.32 ± 2.17 | 0.7289 | ||||
40 Hz | P4 | S | 2.92 ± 0.79 | 6.48 ± 1.91 | 0.00019 | 6 | 11 |
Psuccess | 0.13 ± 0.04 | 0.31 ± 0.07 | 0.00010 | ||||
A | 22.57 ± 2.53 | 19.48 ± 2.38 | 0.6703 | ||||
P6–P7 | S | 10.68 ± 1.35 | 19.20 ± 3.12 | 0.0055 | 4 | 11 | |
Psuccess | 0.44 ± 0.04 | 0.64 ± 0.08 | 3.6e−05 | ||||
A | 23.45 ± 1.40 | 28.98 ± 1.71 | 0.4565 | ||||
P9–P11 | S | 28.61 ± 4.59 | 12.83 ± 1.66 | 5.0e−14 | 10 | 13 | |
Psuccess | 0.77 ± 0.05 | 0.57 ± 0.07 | 6.2e−08 | ||||
A | 34.82 ± 3.08 | 22.34 ± 1.36 | 0.0828 | ||||
100 Hz | P4 | S | 1.04 ± 0.21 | 3.49 ± 0.98 | 0.0054 | 6 | 11 |
Psuccess | 0.08 ± 0.01 | 0.23 ± 0.04 | 0.0004 | ||||
A | 12.65 ± 1.31 | 13.51 ± 1.43 | 0.3767 | ||||
P6–P7 | S | 12.59 ± 1.71 | 22.95 ± 2.39 | 3.8e−06 | 4 | 8 | |
Psuccess | 0.53 ± 0.05 | 0.74 ± 0.05 | 8.0e−06 | ||||
A | 23.15 ± 1.05 | 30.77 ± 1.20 | 0.0014 | ||||
P9–P11 | S | 29.28 ± 4.01 | 8.23 ± 1.52 | 1.17e−10 | 10 | 13 | |
Psuccess | 0.81 ± 0.05 | 0.37 ± 0.06 | 5.6e−15 | ||||
A | 34.78 ± 2.71 | 21.74 ± 1.40 | 0.0012 |
Stimulation trains consisting of 10 pulses at 10, 40, and 100 Hz were applied at P4, P6–P7, and P9–P11 IHCs. S, Psuccess, and A were computed for each pulse. The first pulse values (X1) and the maximum (in case of facilitation) or minimum value (in case of depression) (Xmax(min)) for S, Psuccess, and A are shown for each dataset. The p-values correspond to one-way ANOVA/Friedman test results when no significant differences were found; otherwise, they correspond to the multiple-comparisons post hoc test result for Xmax(min) shown. S and A values are in pA. At all ages, the reported number of cells was obtained from 7–13 mice.