TABLE 1.

Kinetic parameters (K_M and rates for spSPT and scSPT) versus different serine isotopologues

	SpSPT		scSPT
	KM (mM)	Rate (nmol·min−1·mg−1)	Rate (nmol·min−1·mg−1)
1: l-serine	1.56 ± 0.10	386.3 ± 39.7	11.6 ± 1.3
2: [3,3-D]l-serine	2.72 ± 0.29	396.7 ± 13.1	12.2 ± 0.8
3: [2,3,3-D]l-serine	4.09 ± 0.32	176.9 ± 13.0	10.4 ± 2.2
4: [2-13C]l-serine	3.64 ± 0.61	410.6 ± 25.5	11.3 ± 0.8
5: [1,2,3-13C, 2-15N]l-serine	1.79 ± 0.20	440.5 ± 17.9	12.9 ± 1.9