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. 2019 Mar 7;60(5):1005–1019. doi: 10.1194/jlr.M092676

Fig. 1.

Fig. 1.

Changes in hepatic CoA content, Nudt7 mRNA, and activity with fasting. Mice were fasted for 0–48 h and livers were harvested for the measurement of total hepatic CoA levels (A), Nudt7 mRNA (B), and CoA-degrading activity (C) using the Nudt7 substrate, mBB-CoA, as described in the Materials and Methods. Data are reported as the mean (horizontal lines) of measurements on individual mice (circles) ± SEM. ##P < 0.01, ###P < 0.001 relative to the fed state at t = 0.