Fig. 3.

any1Δ genetic interactions with P4-ATPase mutants. A: any1Δ suppresses the cold-sensitive growth of drs2Δ, high-temperature growth defects of neo1-1 and neo1-2, and the synthetic lethality between drs2 and neo1^ts alleles. Both neo1-1^ts and neo1-2^ts can support the viability of any1Δ drs2Δ cells at all temperatures tested except for 37°C. B: Loss of Any1 failed to suppress the synthetic lethality of dnf1,2,3Δ drs2Δ. C: Loss of Any1 can suppress the synthetic lethality of neo1Δ lem3Δ or neo1^ts lem3Δ at all temperatures tested except for 37°C. These images are representative of four independent growth assays.