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Prediction of obstructive CAD per subpopulation. REFINE-SPECT subpopulations were defined by sex (F, M), obesity (nonobese: body mass index < 30 kg/m2, obese: body mass index ≥ 30 kg/m2), stress imaging activity (low: patients undergoing stress-first/stress-only MPI; standard: patients undergoing rest-first/2-d MPI), and stress test type (exercise, pharmacologic). Red dotted line shows overall multicenter AUC as reported in Figure 3. BMI = body mass index; CI = confidence interval.
