(A) Coronal images from 60-y-old woman with stage IV ductal breast carcinoma (blue circles in Fig. 1A, same scanner). SUVmax for 9 evaluable lesions ranged from 3.4 to 5.1 (average, 4.0) for first scan and from 3.1 to 4.9 (average, 4.2) for second scan. Percentage difference was −16% to +16% (average, 3.9%); SUV unit difference was −0.62 to +0.64 (average, 0.15). (B) A 73-y-old woman with stage IV mixed ductal/lobular breast carcinoma (yellow circles in Fig. 1C, different institutions). SUVmax for 17 evaluable lesions was 2.0–12.2 (average, 4.8) for first scan and 1.9–12.0 (average, 4.4) for second scan. Percentage difference was −24% to +25% (average, −7.1%); SUV unit difference was −1.4 to +1.0 (average, −0.39). Normal liver SUVmean was 2.5 (A) and 2.6 (B) in both scans.