FIGURE 1.

Summarized stability data obtained at 21°C. The 0.25 M NaOAc buffer containing 5 mg·mL⁻¹ L-MET was superior to other formulations at maintaining solution stability of ⁸⁹Zr-DFO-cetuximab (A) and ⁸⁹Zr-DFO-trastuzumab (B) during study. Percentage intact radiopharmaceutical was determined by subtracting total area under product peak from total area generated for all peaks in size-exclusion chromatogram and multiplying by factor of 100%. Each data point is average of 3 size-exclusion chromatography runs.