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. 2014 Nov 18;21(3):222–230. doi: 10.1111/cns.12342

Figure 4.

Figure 4

Reduced antigen‐specific reactivity and increased IL‐10 secretion of splenocytes from mice treated with TolDC‐MOG. (A) MOG‐induced proliferative response from mice treated preventively, preclinically, or therapeutically with PBS (vehicle), unpulsed TolDC, or TolDC‐MOG. The data are expressed as stimulation index (SI). (B) Analysis of the antiinflammatory cytokine IL‐10 secretion in supernatants of MOG‐stimulated splenocytes from mice treated preventively, preclinically, or therapeutically with PBS (vehicle), unpulsed TolDC, or TolDC‐MOG. Error bars correspond to SEM. *P < 0.05, **P < 0.01.