Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Feb 5;18(5):954–967. doi: 10.1074/mcp.TIR119.001323

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2019 Yu et al.

Published under exclusive license by The American Society for Biochemistry and Molecular Biology, Inc.

PMC Copyright notice

Fig. 5. — Oxidative stress induces structural changes within the 20S CP. A, Respective distribution of quantified 20S-20S cross-links for proteasomes purified from the three selected baits. The 20S-20S cross-links were decreased significantly in proteasomes from Rpn11 and Rpt6 but remain unchanged in α7 purifications. B, Mapping the 20S-20S cross-links identified from Rpn11 and Rpt6 proteasome purifications to the high-resolution structure of the human 26S proteasome shows distribution of cross-links to the solvent-accessible perimeter of the 20S subcomplex.