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The structure of the 19S RP is impacted by H2O2 stress. A, Respective distribution of quantified 19S-19S cross-links for proteasomes purified from the three selected baits. All cross-links were significantly reduced in α7-purified proteasomes but varied considerably in proteasomes from Rpt6 and Rpn11 purifications. B, 19S-19S cross-links identified from α7-purified proteasomes were mapped to the 26S proteasome high-resolution structure.
