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. 2015 May 21;21(7):585–590. doi: 10.1111/cns.12406

Figure 1.

Figure 1

Effects of PDC (FeTMPyP, 3 mg/kg) on hemorrhagic transformation in ischemic rat brains with early and delayed t‐PA treatments. Rats were treated with t‐PA (10 mg/kg) at 2 and 5 h of MCAO ischemia following 22 and 19 h of reperfusion, respectively. M2/R22, 2 h of MCAO plus 22 h of reperfusion; M5/R19, 5 h of MCAO plus 19 h of reperfusion; (A) brain samples in M2/R22 plus t‐PA groups with or without PDC treatment; (B) brain samples in M/R22 plus t‐PA groups with or without PDC; (C) brain hemoglobin content in M2/R22 groups with t‐PA or t‐PA plus PDC treatments; (D) brain hemoglobin content in M5/R19 groups with t‐PA or t‐PA plus PDC treatments (*P < 0.05, compared to M5/R19 group; # P < 0.05, compared to M5/R19 + t‐PA group). Data are expressed as mean ± SEM (n = 6–11).