Table 5.
Plasma levels of AKT1 protein according to the AKT1 genotypes
| GG | GC | CC | P (GG vs. GC) | P (GG vs. CC) | |
|---|---|---|---|---|---|
| Total (N = 574) | 295 | 173 | 106 | ||
| AKT1 (μmol/L) | 17.0 ± 3.3 | 14.2 ± 2.7 | 12.2 ± 3.8 | <0.0001 | <0.0001 |
| AD with T2D group (n = 112) | 49 | 34 | 29 | ||
| AKT1 (μmol/L) | 16.9 ± 2.8 | 13.7 ± 3.3 | 11.9 ± 3.1 | <0.0001 | <0.0001 |
| AD control group (n = 231) | 110 | 56 | 65 | ||
| AKT1 (μmol/L) | 16.6 ± 2.2 | 14.5 ± 3.2 | 12.4 ± 4.6 | <0.0001 | <0.0001 |
| Healthy control group (n = 231) | 136 | 83 | 12 | ||
| AKT1 (μmol/L) | 17.3 ± 3.7 | 14.3 ± 2.5 | 12.2 ± 4.6 | <0.0001 | <0.0001 |
Bold values represent statistical significance.