Dopamine transporter and TH expression levels are decreased in the putamen of people with major depressive disorder (MDD). Box blots show the expression levels (mean and SE) for DAT (40, 50, 60, and 80 kDa) (A-D) and TH (60 kDa) (E). Protein levels are expressed as a normalized signal in fluorescence arbitrary units (LI-COR Odyssey CLx scanner). C indicates control group; Dx, diagnosis; Norm, normalized signal.
aNot significant (P > .05).
bSignificant (P = .05 to P = .01).
cHighly significant (P = .01 to P = .001).