Table 2.
Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analyses of differentially expressed genes in very early hepatocellular carcinoma tissue samples
| Term | Count | P value | Genes |
|---|---|---|---|
| Mineral absorption | 6 | 4.71E-05 | MT1M, MT1A, MT1H, MT1X, MT1G, MT1F |
| p53 signaling pathway | 6 | 2.88E-04 | CDK1, CDKN2A, RRM2, IGF1, THBS1, IGFBP3 |
| African trypanosomiasis | 4 | 0.002958176 | IDO2, HBA2, HBA1, HBB |
| Tryptophan metabolism | 4 | 0.005127472 | ALDH1B1, IDO2, CYP1A2, INMT |
| Chemical carcinogenesis | 5 | 0.005272955 | CYP3A4, NAT2, HSD11B1, ADH1B, CYP1A2 |
| Malaria | 4 | 0.009039916 | HBA2, HBA1, THBS1, HBB |
| Phagosome | 6 | 0.010951526 | MRC1, MARCO, HLA-DRB4, COLEC11, THBS1, CLEC4M |
| Steroid hormone biosynthesis | 4 | 0.014316303 | CYP3A4, HSD11B1, SRD5A2, CYP1A2 |
| Metabolism of xenobiotics by cytochrome P450 | 4 | 0.027242121 | CYP3A4, HSD11B1, ADH1B, CYP1A2 |
| Salmonella infection | 4 | 0.036531167 | FOS, CCL4L1, CCL4L2, CCL4 |