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. Author manuscript; available in PMC: 2020 Dec 1.
Published in final edited form as: DNA Repair (Amst). 2019 Apr 4;84:102614. doi: 10.1016/j.dnarep.2019.04.002

Figure 3. Genome instability assays.

Figure 3.

A. Recombination rates of rnaseh2-AGS mutants. A recombination reporter consisting of direct LEU2 repeats flanking a URA3 marker was used for fluctuation analysis to determine gene conversion rates. Error bars represent the standard deviation from 3 independent experiments, and fold increase from wild type level is reported above the bars. B. Dinucleotide slippage mutation rate of rnaseh2-AGS mutants. Rates of dinucleotide slippage were determined using a reporter containing an (AG)4 tandem repeat embedded in the LYS2 gene. Fluctuation analysis was used to determine rates, and error bars represent the standard deviation from 3 independent experiments, and fold increase from wild type level is reported above the bars.