Figure 3.

Inhibition and timing of transfer events supports exocytosis-phagocytosis hypothesis. A. Quantification of the frequency of transfer events observed between BMDMs supplemented with different inhibitor antibody combinations. Frequency values represent frequency of events based on number of events in all infected cells, with complete information found in Table I. P values calculated via one tailed proportion test. B. Quantification of the total timespan of each transfer event as well as phagocytosis ingestion time determined by total frames captured. C. Quantification of the total timespan of transfer events compared to the addition of phagocytosis and exocytosis events. Data points represent population average with bars representing population standard deviations. P value calculated as non-significant via unpaired two tailed t-test. D. Timespan between the start of an experiment and the initial frame of transfer events. Events began at 392 min post infection (SD +/− 395 min) with most events occurring before 9 h.