Table 3.

Cox proportional hazards for PSA recurrence-free survival after prostatectomy of established preoperative prognostic parameter and SNW1 expression

Variable	Univariable analysis	Multivariable analysis
Gleason grade biopsy
≥ 4 + 4 vs. ≤3 + 3	6.01 (5.41–6.66) ***	4.05 (3.58–4.58) ***
Preoperative PSA-level (ng/μl)
> 20 vs. < 4	5.12 (4.46–5.89) ***	3.61 (3.00–4.35) ***
cT-stage
T2b vs. T1c	2.16 (1.73–2.66) ***	1.84 (1.62–2.08) ***
SNW1 expression
Strong vs. negative	1.95 (1.69–1.26) ***	1.63 (1.40–1.89) ***
ERG negative subset	2.38 (1.90–2.97) ***	1.88 (1.49–2.35) ***
ERG positive subset	1.81 (1.30–2.60) **	1.48 (1.06–2.14) *

The multivariable model included all the four-univariate factors. Confidence interval (95%) in brackets; asterisk indicate significance level: * p ≤ 0.05, ** p ≤ 0.001, *** p ≤ 0.0001; ERG ETS-related gene