Table 1.
GO and KEGG pathway enrichment analysis of DEGs between non-AS macrophages and AS macrophages
| Term | Description | Count in gene set | P-value |
|---|---|---|---|
| GO:0032007 | negative regulation of TOR signaling | 3 | 0.010 |
| GO:0001666 | response to hypoxia | 5 | 0.014 |
| GO:0007585 | respiratory gaseous exchange | 3 | 0.015 |
| GO:0005622 | intracellular | 16 | 0.003 |
| GO:0097542 | ciliary tip | 3 | 0.022 |
| GO:0031901 | early endosome membrane | 4 | 0.022 |
| GO:0004843 | thiol-dependent ubiquitin-specific protease activity | 4 | 0.009 |
| GO:0005515 | protein binding | 58 | 0.015 |
| GO:0061578 | Lys63-specific deubiquitinase activity | 2 | 0.026 |
| hsa04014 | Ras signaling pathway | 7 | 0.003 |
| hsa04910 | Insulin signaling pathway | 5 | 0.012 |
| hsa04012 | ErbB signaling pathway | 4 | 0.019 |
| hsa04912 | GnRH signaling pathway | 4 | 0.021 |
GO Gene Ontology, KEGG Kyoto Encyclopedia of Genes and Genomes, DEGs differentially expressed genes, AS atherosclerosis