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. Author manuscript; available in PMC: 2020 Jan 1.
Published in final edited form as: J Biomed Inform. 2018 Sep 4;89:56–67. doi: 10.1016/j.jbi.2018.09.001

Table 4:

Predicting Hepatomegaly using the PBC data set

Clinical visits in advanced Model ACC AUC Sens Spec PPV
1 MErf 0.83(0.78,0.86) 0.88(0.83,0.91) 0.86(0.81,0.90) 0.79(0.72,0.83) 0.86(0.82,0.90)
MEgbm 0.83(0.77,0.87) 0.87(0.84,0.90) 0.88(0.80,0.91) 0.76(0.67,0.81) 0.85(0.80,0.89)
MEmob 0.84(0.81,0.87) 0.85(0.81,0.91) 0.86(0.79,0.90) 0.81(0.77,0.84) 0.88(0.86,0.90)
MEctree 0.84(0.78,0.87) 0.85(0.81,0.89) 0.86(0.79,0.90) 0.80(0.63,0.85) 0.87(0.79,0.91)
GLMM 0.85(0.82,0.88) 0.90(0.87,0.92) 0.86(0.79,0.90) 0.85(0.79,0.89) 0.90(0.86,0.93)
GLM 0.85(0.82,0.88) 0.90(0.87,0.93) 0.86(0.80,0.90) 0.84(0.78,0.88) 0.89(0.86,0.92)
GBM 0.85(0.82,0.87) 0.90(0.87,0.92) 0.85(0.79,0.90) 0.86(0.80,0.91) 0.91(0.87,0.94)
RF 0.84(0.81,0.87) 0.90(0.87,0.93) 0.83(0.78,0.89) 0.86(0.81,0.92) 0.90(0.86,0.94)
2 MErf 0.83(0.77,0.87) 0.87(0.80,0.92) 0.85(0.76,0.92) 0.79(0.76,0.86) 0.85(0.80,0.90)
MEgbm 0.83(0.77,0.88) 0.87(0.79,0.91) 0.86(0.78,0.93) 0.78(0.72,0.85) 0.84(0.79,0.89)
MEmob 0.81(0.76,0.88) 0.86(0.80,0.90) 0.84(0.77,0.93) 0.76(0.70,0.82) 0.83(0.77,0.87)
MEctree 0.81(0.76,0.86) 0.85(0.78,0.89) 0.84(0.74,0.91) 0.76(0.71,0.82) 0.83(0.78,0.87)
GLMM 0.82(0.76,0.86) 0.86(0.78,0.90) 0.84(0.74,0.91) 0.80(0.76,0.85) 0.85(0.81,0.89)
GLM 0.78(0.74,0.81) 0.84(0.77,0.87) 0.81(0.73,0.87) 0.74(0.68,0.80) 0.81(0.74,0.86)
GBM 0.79(0.74,0.82) 0.85(0.81,0.88) 0.80(0.72,0.87) 0.78(0.71,0.85) 0.83(0.78,0.87)
RF 0.81(0.77,0.85) 0.87(0.81,0.91) 0.81(0.73,0.90) 0.81(0.73,0.87) 0.85(0.78,0.89)
3 MErf 0.83(0.74,0.88) 0.87(0.79,0.91) 0.88(0.74,0.94) 0.78(0.67,0.84) 0.84(0.75,0.88)
MEgbm 0.83(0.74,0.87) 0.87(0.79,0.90) 0.88(0.76,0.94) 0.77(0.63,0.82) 0.83(0.74,0.87)
MEmob 0.82(0.74,0.86) 0.86(0.80,0.89) 0.87(0.76,0.93) 0.75(0.69,0.81) 0.82(0.77,0.86)
MEctree 0.82(0.75,0.86) 0.85(0.80,0.89) 0.86(0.74,0.92) 0.77(0.71,0.82) 0.83(0.79,0.86)
GLMM 0.82(0.78,0.87) 0.87(0.82,0.91) 0.84(0.77,0.91) 0.80(0.74,0.85) 0.84(0.79,0.88)
GLM 0.77(0.72,0.81) 0.83(0.77,0.86) 0.78(0.67,0.82) 0.77(0.70,0.83) 0.81(0.75,0.86)
GBM 0.78(0.74,0.82) 0.84(0.79,0.88) 0.77(0.70,0.86) 0.79(0.73,0.89) 0.82(0.78,0.89)
RF 0.78(0.73,0.83) 0.87(0.83,0.90) 0.76(0.69,0.82) 0.81(0.70,0.87) 0.83(0.76,0.88)
4 MErf 0.81(0.64,0.86) 0.85(0.65,0.89) 0.83(0.67,0.88) 0.78(0.55,0.85) 0.83(0.69,0.89)
MEgbm 0.81(0.65,0.86) 0.85(0.63,0.89) 0.84(0.71,0.90) 0.76(0.53,0.84) 0.82(0.68,0.88)
MEmob 0.82(0.75,0.86) 0.86(0.78,0.90) 0.84(0.76,0.89) 0.80(0.71,0.83) 0.84(0.79,0.87)
MEctree 0.82(0.65,0.87) 0.84(0.61,0.89) 0.84(0.72,0.91) 0.78(0.55,0.83) 0.83(0.70,0.87)
GLMM 0.85(0.79,0.88) 0.87(0.81,0.90) 0.86(0.81,0.92) 0.83(0.76,0.87) 0.86(0.82,0.89)
GLM 0.73(0.67,0.79) 0.78(0.71,0.85) 0.73(0.66,0.81) 0.73(0.64,0.83) 0.78(0.69,0.85)
GBM 0.73(0.68,0.79) 0.78(0.72,0.84) 0.72(0.58,0.84) 0.74(0.66,0.83) 0.78(0.72,0.83)
RF 0.76(0.71,0.81) 0.80(0.73,0.86) 0.76(0.69,0.82) 0.75(0.64,0.83) 0.79(0.72,0.86)
5 MErf 0.85(0.80,0.89) 0.88(0.84,0.91) 0.87(0.78,0.93) 0.83(0.79,0.90) 0.87(0.83,0.92)
MEgbm 0.85(0.79,0.88) 0.89(0.85,0.91) 0.87(0.76,0.92) 0.83(0.79,0.89) 0.87(0.83,0.92)
MEmob 0.84(0.76,0.89) 0.87(0.77,0.91) 0.85(0.74,0.94) 0.83(0.77,0.88) 0.86(0.81,0.91)
MEctree 0.86(0.78,0.90) 0.88(0.85,0.91) 0.87(0.78,0.92) 0.84(0.79,0.89) 0.87(0.82,0.92)
GLMM 0.85(0.81,0.90) 0.86(0.80,0.92) 0.86(0.79,0.92) 0.85(0.77,0.91) 0.88(0.82,0.93)
GLM 0.67(0.61,0.73) 0.73(0.62,0.81) 0.65(0.58,0.78) 0.70(0.60,0.79) 0.73(0.66,0.81)
GBM 0.70(0.64,0.76) 0.74(0.68,0.81) 0.67(0.56,0.76) 0.73(0.61,0.87) 0.76(0.69,0.85)
RF 0.74(0.70,0.78) 0.79(0.76,0.83) 0.75(0.65,0.83) 0.74(0.65,0.83) 0.78(0.72,0.84)
6 MErf 0.82(0.78,0.86) 0.87(0.82,0.90) 0.85(0.75,0.92) 0.80(0.75,0.84) 0.83(0.78,0.87)
MEgbm 0.83(0.78,0.86) 0.87(0.82,0.90) 0.85(0.77,0.91) 0.80(0.76,0.85) 0.83(0.79,0.87)
MEmob 0.82(0.79,0.85) 0.86(0.82,0.90) 0.84(0.78,0.92) 0.79(0.75,0.82) 0.82(0.79,0.85)
MEctree 0.82(0.74,0.86) 0.87(0.81,0.90) 0.83(0.67,0.92) 0.80(0.76,0.84) 0.83(0.78,0.87)
GLMM 0.83(0.79,0.86) 0.85(0.80,0.89) 0.84(0.77,0.89) 0.82(0.77,0.86) 0.84(0.81,0.87)
GLM 0.66(0.57,0.72) 0.69(0.57,0.78) 0.62(0.56,0.68) 0.69(0.57,0.77) 0.70(0.58,0.79)
GBM 0.65(0.57,0.72) 0.68(0.59,0.74) 0.65(0.52,0.76) 0.66(0.52,0.83) 0.68(0.58,0.80)
RF 0.71(0.63,0.78) 0.76(0.68,0.82) 0.71(0.60,0.81) 0.73(0.61,0.82) 0.74(0.63,0.84)
7 MErf 0.82(0.80,0.85) 0.88(0.83,0.92) 0.84(0.78,0.90) 0.81(0.76,0.86) 0.84(0.80,0.90)
MEgbm 0.82(0.78,0.85) 0.88(0.83,0.91) 0.83(0.76,0.89) 0.82(0.77,0.86) 0.84(0.80,0.89)
MEmob 0.82(0.77,0.85) 0.87(0.79,0.91) 0.82(0.72,0.89) 0.81(0.75,0.87) 0.84(0.78,0.89)
MEctree 0.82(0.80,0.85) 0.89(0.84,0.92) 0.83(0.76,0.89) 0.81(0.77,0.86) 0.84(0.80,0.89)
GLMM 0.82(0.71,0.86) 0.84(0.72,0.88) 0.85(0.74,0.92) 0.78(0.63,0.84) 0.82(0.71,0.88)
GLM 0.62(0.58,0.70) 0.61(0.57,0.68) 0.63(0.49,0.80) 0.61(0.52,0.74) 0.66(0.60,0.71)
GBM 0.65(0.57,0.70) 0.66(0.57,0.73) 0.66(0.47,0.80) 0.63(0.51,0.75) 0.68(0.62,0.74)
RF 0.67(0.57,0.72) 0.70(0.60,0.75) 0.69(0.57,0.82) 0.64(0.52,0.78) 0.70(0.58,0.78)