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. Author manuscript; available in PMC: 2019 May 2.
Published in final edited form as: J Am Chem Soc. 2018 Nov 5;140(45):15525–15534. doi: 10.1021/jacs.8b10238

Table 1.

Anti-Markovnikov Hydroarylation with Pyridyl Radicals: Scope of the Functionalized Olefinaa

graphic file with name nihms-1014078-t0010.jpg
a

Performed with [Ir(ppy)2 dtbbpy]PF6 (1 mol %), Hantzsch ester (1.3 mmol), 2-bromo-6-methylpyridine (1 mmol), alkene (3 mmol), and CySH (5 mol %) in 2,2,2-trifluoroethanol (0.1 M) at 23 °C for 16 h. Isolated yields are shown.

b

The reaction was performed on a 0.1 mmol scale.

c

The reaction was performed on a 0.25 mmol scale.