Table 1.
History of development of modern hyperthermic intraperitoneal chemotherapy procedure
| Year | Development |
|---|---|
| 1979-1980 | TIFS developed to deliver heated chemotherapy into the peritoneum and tested in humans for administration of HIPEC for locally advanced abdominal malignancy[4] |
| Mid to late 1980s | Dr. Sugarbaker reported survival benefits in patients with peritoneal dissemination[1] |
| 1995 | Dr. Sugarbaker standardized the procedure and described stepwise approach to cytoreduction[5] |
| 2016 | LE-HIPEC technique described where the HIPEC given after the closure of the abdominal wound and spread with the help of laparoscopic approach[6] |
HIPEC=Hyperthermic intraperitoneal chemotherapy, TIFS=Thermal transfusion infiltration system, LE=Laparoscopy-enhanced