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. 2019 Jan-Mar;35(1):3–11. doi: 10.4103/joacp.JOACP_93_18

Table 1.

History of development of modern hyperthermic intraperitoneal chemotherapy procedure

Year Development
1979-1980 TIFS developed to deliver heated chemotherapy into the peritoneum and tested in humans for administration of HIPEC for locally advanced abdominal malignancy[4]
Mid to late 1980s Dr. Sugarbaker reported survival benefits in patients with peritoneal dissemination[1]
1995 Dr. Sugarbaker standardized the procedure and described stepwise approach to cytoreduction[5]
2016 LE-HIPEC technique described where the HIPEC given after the closure of the abdominal wound and spread with the help of laparoscopic approach[6]

HIPEC=Hyperthermic intraperitoneal chemotherapy, TIFS=Thermal transfusion infiltration system, LE=Laparoscopy-enhanced