Table 4.
Associations between allergens and severity disease diagnosed by component-resolved diagnostics
| Asthmaa | Rhinitis | |||||
|---|---|---|---|---|---|---|
| Mild (N = 18) | Moderate-severe (N = 7) | p | Mild (N = 59) | Moderate-severe (N = 36) | p | |
| House dust mites | ||||||
| Der p 1 | 11 (68.8) | 4 (57.1) | 0.657 | 25 (43.1) | 17 (47.2) | 0.831 |
| Der p 2 | 12 (75.0) | 4 (57.1) | 0.626 | 25 (43.1) | 26 (72.2) | 0.010 |
| Der f 1 | 11 (68.8) | 4 (57.1) | 0.657 | 23 (39.7) | 16 (44.4) | 0.672 |
| Der f 2 | 12 (75.0) | 3 (42.9) | 0.182 | 25 (43.1) | 25 (69.4) | 0.019 |
| Lep d 2 | 7 (43.8) | 3 (42.9) | 1.000 | 7 (12.1) | 12 (33.3) | 0.018 |
| Pollens | ||||||
| Ole e 1 | 9 (60.0) | 4 (57.1) | 1.000 | 25 (43.1) | 14 (41.2) | 1.000 |
| Ole e 9 | 1 (6.3) | 0 (0.0) | 1.000 | 1 (1.7) | 1 (2.8) | 1.000 |
| Art v 1 | 1 (6.3) | 0 (0.0) | 1.000 | 5 (8.8) | 4 (11.1) | 0.731 |
| Pla l 1 | 0 (0.0) | 0 (0.0) | – | 2 (3.4) | 3 (8.3) | 0.368 |
| Phl p 1 | 7 (43.8) | 1 (14.3) | 0.345 | 17 (29.3) | 16 (44.4) | 0.183 |
| Phl p 5 | 1 (6.3) | 0 (0.0) | 1.000 | 6 (10.3) | 5 (13.9) | 0.744 |
| Pla a 1 + 2 | 0 (0.0) | 1 (14.3) | 0.304 | 4 (6.9) | 1 (2.8) | 0.646 |
| Par j 2 | 2 (12.5) | 2 (28.6) | 0.557 | 8 (14) | 7 (19.4) | 0.567 |
| Sal k 1 | 0 (0.0) | 0 (0.0) | – | 1 (1.7) | 2 (5.6) | 0.556 |
| Cup s 1 | 1 (6.3) | 1 (16.7) | 0.480 | 6 (10.5) | 3 (8.3) | 1.000 |
| Molds | ||||||
| Alt a 1 | 2 (12.5) | 1 (14.3) | 1.000 | 9 (15.5) | 9 (25.0) | 0.289 |
| Panallergens | ||||||
| Pho d 2 | ||||||
| Che a 3 | ||||||
| Pru p 3 | ||||||
| Der p 10 | 0 (0.0) | 1 (16.7) | 0.273 | 0 (0.0) | 2 (5.6) | 0.147 |
| Pen a 1 | 1 (6.3) | 0 (0.0) | 1.000 | 2 (3.4) | 2 (5.7) | 0.630 |
p values in italics correspond to significant differences at a bilateral alpha value of 0.05
Positive sensitizations, No. (%)
aWith or without concomitant rhinitis