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Comparison of IC50 determined by antiproliferation and antitopoisomerase tests on HaCaT and WEHI‐3B cells
| Drug | Antiproliferation test | Antitopoisomerase I test | ||
|---|---|---|---|---|
| WEHI‐3B (µm) | HaCaT (µm) | WEHI‐3B (µm) | HaCaT (µm) | |
| Doxorubicin | 0.13 | 0.017 | 0.3 (2.3) a | 5.5 (323.5) |
| Camptothecin | 0.0069 | 0.0051 | 50.41 (7246) | 86.2 (18862) |
| Ciprofloxacin | 87.35 | 35.72 | 302.9 (3.46) | 548 (15.3) |
a Numbers in brackets are the ratios of the IC 50 values (antitopoisomerase I:antiproliferation test).
