Figure 2.

  Aggregated amyloid beta (Aβ) treatment of bone marrow‐derived mesenchymal stem cells (BM‐MSC) produced no significant changes in apoptosis and cell cycling. (a) BM‐MSCs treated with aggregated 5 µm Aβs at 2 dpp and analysed for apoptotic cells after 5 days incubation by propidium iodide/Annexin‐V staining and fluorescence‐activated cell sorting method. BM‐MSC cultures treated with Aβs show no change in apoptosis forward scatter profiles compared to controls. (b) Cell cycle profiling confirmed that there were no significant changes in the proportion of BM‐MSC at S phase of the cell cycle in treated versus control conditions. The graphs show mean ± standard error of the mean from one representative of three different experiments done in triplicate.