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. 2008 Oct 19;41(6):843–858. doi: 10.1111/j.1365-2184.2008.00564.x

Figure 4.

Figure 4

Mean survival (a) and the Kaplan Meier curve of survival (b) of mice transplanted with either hESC derived ILCs (n = 42), a human fibroblast cell line (hFCs, n = 21) or undifferentiated hESC (uhESC, n = 6). For the Kaplan Meier curve (4B), the log‐rank (Mantel‐Cox) test of the equality of survival distributions for the different levels of group denotes P < 0.0001. Of the 42 animals transplanted with ILCs, 7 were found dead at various time points, 19 healthy mice were euthanized at defined time points after 50 days post‐transplant then 3 and 2 mice were euthanized due to illness before or after 50 days post‐transplant, respectively. Lastly, 11 healthy mice in this group were euthanized at predetermined time points before 50 days post transplant and were not included in this graph. Human serum C‐peptide was also determined in mice transplanted with ILCs (n = 12) or control mice implanted with hFCs (n = 9, c). *P < 0.0001, †P < 0.042.