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Effect of EA extract and I3‐O‐R‐ on caspase‐3 activity in K562 cells. Lysates prepared from cells treated with EA extract and I3‐O‐R for 24 and 48 h, were assayed for in vitro caspase‐3 activity. The rate of cleavage of the caspase substrate DEVD‐pNA was measured at 405 nm. The results are presented as the mean ± SD. The experiments were done in triplicate. *P < 0.05 means a significant difference between the control and treated cells. Control: cells treated by the vehicle only.
