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Effect of EA extract and I3‐O‐R on caspase‐8 activity in K562 cells. Lysates obtained from cells treated with the EA extract and I3‐O‐R 24 and 48 h were assayed for in vitro caspase‐8 activity. The rate of cleavage of the caspase substrate IETD‐pNA measured at 405 nm. The results are presented as the mean ± SD. The experiments were done in triplicate. *P < 0.05 means a significant difference between the control and treated cells. Control: cells treated by the vehicle only.
