Figure 1.

Cell morphology changes after crosstalk between chondrocytes and osteoblasts. non‐contact and contact crosstalk between chondrocytes and osteoblasts, (b) representative cell morphologies in contact cell–cell co‐culture using chondrocytes from RFP‐labelled mice and osteoblasts from GFP‐labelled mice, and (c) unchanged cell numbers in all groups. Norm, normoxia; Hypo, hypoxia; Mo, monoculture; Co, co‐culture; NS, no significant difference; (d) changes of cell sizes. *P < 0.05 for the difference between the monoculture group and co‐culture group (n = 4).