Table 1.
Effects of administration of HgCl2 alone and in combination with donor BMCs on renal tubular injury score and serum urea nitrogen
| Parameter | n | Pre‐HgCl2 | Post‐HgCl2 and male BMCs | ||
|---|---|---|---|---|---|
| Day 3 | Day 7 | Day 28 | |||
| Tubular injury score | |||||
| Group CON | 5 | 0.12 ± 0.01 | 0.10 ± 0.02 | 0.11 ± 0.02 | 0.11 ± 0.02 |
| Group mBM | 5 | 0.11 ± 0.01 | 0.11 ± 0.01 | 0.12 ± 0.01 | 0.10 ± 0.02 |
| Group HgCl2 | 5 | 0.12 ± 0.01 | 3.66 ± 0.04[Link], [Link], [Link] | 1.37 ± 0.02[Link], [Link], [Link] | 0.10 ± 0.02 |
| Group HgCl2 + mBM | 5 | 0.10 ± 0.02 | 3.72 ± 0.04[Link], [Link], [Link] | 1.4 ± 0.01[Link], [Link], [Link] | 0.11 ± 0.02 |
| Serum urea nitrogen (mg/dL) | |||||
| Group CON | 5 | 20.1 ± 1.9 | 17.8 ± 2.6 | 19.1 ± 2.2 | 17.7 ± 2.5 |
| Group mBM | 5 | 18.2 ± 2.2 | 18.5 ± 2.7 | 18.7 ± 2.3 | 17.1 ± 1.8 |
| Group HgCl2 | 5 | 21.3 ± 2.2 | 69.1 ± 4.2[Link], [Link], [Link] | 44.7 ± 2.0[Link], [Link], [Link] | 18.8 ± 2.1 |
| Group HgCl2 + mBM | 5 | 20.1 ± 2.7 | 70.4 ± 2.6[Link], [Link], [Link] | 48.4 ± 2.9[Link], [Link], [Link] | 18.5 ± 2.0 |
Values are means ± SEM. *P < 0.05 versus the same group at pre‐HgCl2 period;†P < 0.05 versus group CON at the corresponding time point;‡P < 0.05 versus group mBM at the corresponding time point. BMCs, bone marrow cells; CON, control; mBM, male bone marrow.