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. 2009 Jul 10;42(5):602–616. doi: 10.1111/j.1365-2184.2009.00626.x
graphic file with name CPR-42-602-e027.jpg concentration of O2 at saturation condition, mmol/mm3
Cm oxygen concentration at half‐maximal consumption, mmol/mm3
dc mass density, ng/mm3
DP number of grid points for m domain discretization of PBE model
f(m) division probability density function, 1/ng
Κ saturation capacity of generalized logistic eqn (1), cells
m single cell mass, ng
m mother cell mass, ng
m max maximum cell mass value considered in numerical solution
N cell number, cells
N 0 initial cell number, cells
NExp cell number experimentally evaluated, cells
NTh cell number evaluated from the adopted models, cells
p partitioning function
q coefficient appearing in symmetric beta function
r rate constant of generalized logistic eqn (1), d−1 cells1–α
t time, d
V total cultivation volume, mm3
Greek letters
α parameter of generalized logistic eqn (1)
αP order of the power law given in eqn (12)
β(q, q) symmetric beta function
β parameter of generalized logistic eqn (1)
ϕ occupied area by cells and interstices, mm2
ϕa Petri dish area, mm2
Φ geometric limiting factor
Γ(q) gamma function
γ parameter of generalized logistic eqn (1)
γΜ distribution defined in eqn (9), 1/ng
ΓΜ division rate function, 1/d
µ average mass of dividing cells in eqn (10), ng
µ0 mean value of initial cell mass distribution in eqn (3), ng
µ′ maximum rate of cell growth, ng/(mm2 h)
µc catabolic rate, 1/h
ν time rate of change of cell mass m, ng/h
σ standard deviation of the Gaussian distribution f(m) defined in eqn (10), ng
σ0 standard deviation of the initial cell mass distribution defined in eqn (3), ng
ψ cell distribution function, cells/(ng mm3)