|
concentration of O2 at saturation condition, mmol/mm3
|
Cm
|
oxygen concentration at half‐maximal consumption, mmol/mm3
|
dc
|
mass density, ng/mm3
|
DP
|
number of grid points for m domain discretization of PBE model |
f(m) |
division probability density function, 1/ng |
Κ
|
saturation capacity of generalized logistic eqn (1), cells |
m
|
single cell mass, ng |
m′ |
mother cell mass, ng |
m
max
|
maximum cell mass value considered in numerical solution |
N
|
cell number, cells |
N
0
|
initial cell number, cells |
NExp
|
cell number experimentally evaluated, cells |
NTh
|
cell number evaluated from the adopted models, cells |
p
|
partitioning function |
q
|
coefficient appearing in symmetric beta function |
r
|
rate constant of generalized logistic eqn (1), d−1 cells1–α
|
t
|
time, d
|
V
|
total cultivation volume, mm3
|
Greek letters |
α |
parameter of generalized logistic eqn (1)
|
αP
|
order of the power law given in eqn (12)
|
β(q, q) |
symmetric beta function |
β |
parameter of generalized logistic eqn (1)
|
ϕ |
occupied area by cells and interstices, mm2
|
ϕa
|
Petri dish area, mm2
|
Φ |
geometric limiting factor |
Γ(q) |
gamma function |
γ |
parameter of generalized logistic eqn (1)
|
γΜ
|
distribution defined in eqn (9), 1/ng |
ΓΜ
|
division rate function, 1/d |
µ |
average mass of dividing cells in eqn (10), ng |
µ0
|
mean value of initial cell mass distribution in eqn (3), ng |
µ′ |
maximum rate of cell growth, ng/(mm2 h) |
µc
|
catabolic rate, 1/h |
ν
|
time rate of change of cell mass m, ng/h |
σ |
standard deviation of the Gaussian distribution f(m) defined in eqn (10), ng |
σ0
|
standard deviation of the initial cell mass distribution defined in eqn (3), ng |
ψ |
cell distribution function, cells/(ng mm3) |